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BioLiP

Structure of PDB 1hcq Chain E Binding Site BS01

Receptor Information
>1hcq Chain E (length=74) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCT
IDKNRRKSCQACRLRKCYEVGMMK
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1hcq The crystal structure of the estrogen receptor DNA-binding domain bound to DNA: how receptors discriminate between their response elements.
Resolution2.4 Å
Binding residue
(original residue number in PDB)		G16 Y17 H18 Y19 K28 K32
Binding residue
(residue number reindexed from 1)		G16 Y17 H18 Y19 K28 K32
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0008270 zinc ion binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:1hcq, PDBe:1hcq, PDBj:1hcq
PDBsum1hcq
PubMed8221895
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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