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BioLiP

Structure of PDB 2hap Chain D Binding Site BS01

Receptor Information
>2hap Chain D (length=75) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KRNRIPLRCTICRKRKVKCDKLRPHCQQCTKTGVAHLCHYMEQTWAEEAE
KELLKDNELKKLRERVKSLEKTLSK
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2hap Structure of HAP1-18-DNA implicates direct allosteric effect of protein-DNA interactions on transcriptional activation.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		R57 N58 R59 R70 K71 W100
Binding residue
(residue number reindexed from 1)		R2 N3 R4 R15 K16 W45
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003700 DNA-binding transcription factor activity
GO:0008270 zinc ion binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:2hap, PDBe:2hap, PDBj:2hap
PDBsum2hap
PubMed9886287
UniProtP0CS82|HAP1_YEASX Heme-responsive zinc finger transcription factor HAP1 (Gene Name=HAP1)

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