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Structure of PDB 8f6b Chain C Binding Site BS01

Receptor Information >8f6b Chain C (length=404) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure] VAREALVDLCRRRHFLSGTPQQLSTAALLSGCHARFGPLGVELRKNLASQ WWSSMVVFREQVFAVDSLHQEPGSSQPRDSAFRLVSPESIREILQDREPS KEQLVAFLENLLKTSGKLRATLLHGALEHYVNCLDLVNRKLPFGLAQIGV CFHPVTRVGEKTEASLVWFTPTRTSSQWLDFWLRHRLLWWRKFAMSPSNF SSADCQDELGRKGSKLYYSFPWGKEPIETLWNLGDQELLHTYPGNVSTIQ GRDGRKNVVPCVLSVSGDVDLGTLAYLYDSFQQRKVLKLHPCLAPIKVAL DVGKGPTVELRQVCQGLLNELLENGISVWPGYSETVHSSLEQLHSKYDEM SVLFSVLVTETTLENGLIQLRSRDTTMKEMMHISKLRDFLVKYLASASNV AAAL

Ligand information >8f6b Chain I (length=18) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure] ctggtaggcgcctaccag

Receptor-Ligand Complex Structure Global view Local view Structure summary [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] PDB 8f6b Structure-specific roles for PolG2-DNA complexes in maintenance and replication of mitochondrial DNA. Resolution 2.75 Å Binding residue (original residue number in PDB) T366 R370 T394 H396 Binding residue (residue number reindexed from 1) T307 R311 T335 H337

Enzymatic activity Enzyme Commision number ?

Gene Ontology Molecular Function GO:0003677 DNA binding GO:0003690 double-stranded DNA binding GO:0003887 DNA-directed DNA polymerase activity GO:0030337 DNA polymerase processivity factor activity GO:0042802 identical protein binding GO:0070182 DNA polymerase binding

	Biological Process
GO:0001701	in utero embryonic development
GO:0006260	DNA replication
GO:0006261	DNA-templated DNA replication
GO:0006264	mitochondrial DNA replication
GO:0006281	DNA repair
GO:0007005	mitochondrion organization
GO:0032042	mitochondrial DNA metabolic process
GO:0071897	DNA biosynthetic process
GO:1900264	positive regulation of DNA-directed DNA polymerase activity

	Cellular Component
GO:0005739	mitochondrion
GO:0005759	mitochondrial matrix
GO:0005760	gamma DNA polymerase complex
GO:0042645	mitochondrial nucleoid

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