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Structure of PDB 8bf5 Chain C Binding Site BS01

Receptor Information >8bf5 Chain C (length=729) Species: 1601067 (Influenza B virus (B/Memphis/13/2003)) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure] MTLAKIELLKQLLRDNEAKTVLKQTTVDQYNIIRKFNTSRIEKNPSLRMK WAMCSNFPLALTKGDMANRIPLEYKGIQLKTNAEDIGTKGQMCSIAAVTW WNTYGPIGDTEGFERVYESFFLRKMRLDNATWGRITFGPVERVRKRVLLN PLTKEMPPDEASNVIMEILFPKEAGIPRESTWIHRELIKEKREKLKGTMI TPIVLAYMLERELVARRRFLPVAGATSAEFIEMLHCLQGENWRQIYHPGG NKLTESRSQSMIVACRKIIRRSIVASNPLELAVEIANKTVIDTEPLKSCL AAIDGGDVACDIIRAALGLKIRQRQRFGRLELKRISGRGFKNDEEILIGN GTIQKIGIWDGEEEFHVRCGECRGILKKSKMKLEKLLINSAKKEDMRDLI ILCMVFSQDTRMFQGVRGEINFLNRAGQLLSPMYQLQRYFLNRSNDLFDQ WGYEESPKASELHGINESMNASDYTLKGVVVTRNKVSITKNLSLIKRTGE VIMGANDVSELESQAQLMITYDTPKMWEMGTTKELVQNTYQWVLKNLVTL KAQFLLGKEDMFQWDAFEAFESIIPQKMAGQYSGFARAVLKQMRDQEVMK TDQFIKLLPFCFSPPKLRSNGEPYQFLKLVLKGGGENFIEVRKGSPLFSY NPQTEVLTICGRMMSLKGKIEDEERNRSMGNAVLAGFLVSGKYDPDLGDF KTIEELEKLKPGEKANILLYQGKPVKVVK

Ligand information >8bf5 Chain R (length=12) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure] aacugagaaagc ............

Receptor-Ligand Complex Structure Global view Local view Structure summary [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] PDB 8bf5 Direct observation of backtracking by influenza A and B polymerases upon consecutive incorporation of the nucleoside analog T1106. Resolution 2.96 Å Binding residue (original residue number in PDB) R40 K43 Y207 R216 R218 Binding residue (residue number reindexed from 1) R40 K43 Y207 R216 R218

Enzymatic activity Enzyme Commision number ?

Gene Ontology Molecular Function GO:0003723 RNA binding GO:0003968 RNA-dependent RNA polymerase activity

	Biological Process
GO:0001172	RNA-templated transcription
GO:0006351	DNA-templated transcription
GO:0006370	7-methylguanosine mRNA capping
GO:0019083	viral transcription
GO:0039523	symbiont-mediated suppression of host mRNA transcription via inhibition of RNA polymerase II activity
GO:0039694	viral RNA genome replication
GO:0075526	cap snatching

	Cellular Component
GO:0033650	host cell mitochondrion
GO:0042025	host cell nucleus
GO:0044423	virion component

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