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Structure of PDB 7uix Chain C Binding Site BS01

Receptor Information >7uix Chain C (length=580) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure] ENFTTNLNQLARVGGIDPLIGREKELERAIQVLCRRRKNNPLLVGESGVG KTAIAEGLAWRIVQGDVPEVMADCTIYSLDIGSLLAGTKYRGDFEKRFKA LLKQLEQDTNSILFIDEIHTIIGAGAASGGQVDAANLIKPLLSSGKIRVI GSTTYQEFSNIFEKDRALARRFQKIDITEPSIEETVQIINGLKPKYEAHH DVRYTAKAVRAAVELAVKYINDRHLPDKAIDVIDEAGARARLMPVSKRKK TVNVADIESVVARIARIPEKSVSQSDRDTLKNLGDRLKMLVFGQDKAIEA LTEAIKMARAGLGHEHKPVGSFLFAGPTGVGKTEVTVQLSKALGIELLRF DMSEYMERHTVSRLIGAPPGYVGFDQGGLLTDAVIKHPHAVLLLDEIEKA HPDVFNILLQVMDNGTLTDNNGRKADFRNVVLVMTTNAGVRETERKSIGL IHQDNSTDAMEEIKKIFTPEFRNRLDNIIWFDHLSTDVIHQVVDKFIVEL QVQLDQKGVSLEVSQEARNWLAEKGYDRAMGARPMARVIQDNLKKPLANE LLFGSLVDGGQVTVALDKEKNELTYGFQSA

Ligand information >7uix Chain S (length=25) Species: 562 (Escherichia coli) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure] GKTNDWLDFDQLAEEKVRDALKPPS

Receptor-Ligand Complex Structure Global view Local view Structure summary [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] PDB 7uix AAA+ protease-adaptor structures reveal altered conformations and ring specialization. Resolution 3.24 Å Binding residue (original residue number in PDB) K258 H528 G539 Y540 V541 Binding residue (residue number reindexed from 1) K89 H359 G370 Y371 V372

Enzymatic activity Enzyme Commision number ?

Gene Ontology Molecular Function GO:0004176 ATP-dependent peptidase activity GO:0005515 protein binding GO:0005524 ATP binding GO:0016887 ATP hydrolysis activity

	Biological Process
GO:0006508	proteolysis
GO:0006515	protein quality control for misfolded or incompletely synthesized proteins
GO:0006979	response to oxidative stress
GO:0034605	cellular response to heat
GO:0043335	protein unfolding

	Cellular Component
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0009368	endopeptidase Clp complex

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