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Structure of PDB 1af6 Chain C Binding Site BS01

Receptor Information >1af6 Chain C (length=421) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure] VDFHGYARSGIGWTGSGGEQQCFQTTGAQSKYRLGNECETYAELKLGQEV WKEGDKSFYFDTNVAYSVAQQNDWEATDPAFREANVQGKNLIEWLPGSTI WAGKRFYQRHDVHMIDFYYWDISGPGAGLENIDVGFGKLSLAATRSSEAG GSSSFASNNIYDYTNETANDVFDVRLAQMEINPGGTLELGVDYGRANLRD NYRLVDGASKDGWLFTAEHTQSVLKGFNKFVVQYATDSMTSQGKGLSQGS GVAFDNEKFAYNINNNGHMLRILDHGAISMGDNWDMMYVGMYQDINWDND NGTKWWTVGIRPMYKWTPIMSTVMEIGYDNVESQRTGDKNNQYKITLAQQ WQAGDSIWSRPAIRVFATYAKWDEKWGYDYTGNADNNANFGKAVPADFNG GSFGRGDSDEWTFGAQMEIWW

Ligand information Ligand ID GLC InChI InChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6+/m1/s1 InChIKey WQZGKKKJIJFFOK-DVKNGEFBSA-N SMILES Software SMILES OpenEye OEToolkits 1.5.0 C(C1C(C(C(C(O1)O)O)O)O)O OpenEye OEToolkits 1.5.0 C([C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)O)O)O)O)O CACTVS 3.341 OC[CH]1O[CH](O)[CH](O)[CH](O)[CH]1O CACTVS 3.341 OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O ACDLabs 10.04 OC1C(O)C(OC(O)C1O)CO Formula C6 H12 O6 Name alpha-D-glucopyranose; alpha-D-glucose; D-glucose; glucose ChEMBL CHEMBL423707 DrugBank ZINC ZINC000003861213 PDB chain 1af6 Chain F Residue 1 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure Global view Local view Structure summary [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] PDB 1af6 Channel specificity: structural basis for sugar discrimination and differential flux rates in maltoporin. Resolution 2.4 Å Binding residue (original residue number in PDB) R8 Y41 E43 R82 R109 D116 Y118 Binding residue (residue number reindexed from 1) R8 Y41 E43 R82 R109 D116 Y118 Annotation score 3

Enzymatic activity Enzyme Commision number ?

Gene Ontology Molecular Function GO:0001618 virus receptor activity GO:0005363 maltose transmembrane transporter activity GO:0005515 protein binding GO:0015144 carbohydrate transmembrane transporter activity GO:0015288 porin activity GO:0042958 maltodextrin transmembrane transporter activity

	Biological Process
GO:0006811	monoatomic ion transport
GO:0006974	DNA damage response
GO:0015768	maltose transport
GO:0015774	polysaccharide transport
GO:0034219	carbohydrate transmembrane transport
GO:0042956	maltodextrin transmembrane transport
GO:0046718	symbiont entry into host cell
GO:1904981	maltose transmembrane transport

	Cellular Component
GO:0009279	cell outer membrane
GO:0016020	membrane
GO:0046930	pore complex
GO:0106234	outer membrane protein complex

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