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Structure of PDB 8hhq Chain B Binding Site BS01

Receptor Information >8hhq Chain B (length=249) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure] ESADLRALAKHLYDSYIKSFPLTKAKARAILTGKDKSPFVIYDMNSLMMG EDKIKKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLK YGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFE FAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALEL QLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTHPLLQEIYK

Ligand information Ligand ID GOA InChI InChI=1S/C2H4O3/c3-1-2(4)5/h3H,1H2,(H,4,5) InChIKey AEMRFAOFKBGASW-UHFFFAOYSA-N SMILES Software SMILES ACDLabs 12.01 O=C(O)CO OpenEye OEToolkits 1.7.0 C(C(=O)O)O CACTVS 3.370 OCC(O)=O Formula C2 H4 O3 Name GLYCOLIC ACID; HYDROXYACETIC ACID; HYDROXYETHANOIC ACID ChEMBL CHEMBL252557 DrugBank DB03085 ZINC ZINC000004658557 PDB chain 8hhq Chain B Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure Global view Local view Structure summary [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] PDB 8hhq Covalent Modifier Discovery Using Hydrogen/Deuterium Exchange-Mass Spectrometry. Resolution 2.4 Å Binding residue (original residue number in PDB) C285 Y327 H449 Binding residue (residue number reindexed from 1) C66 Y108 H230 Annotation score 1

Enzymatic activity Enzyme Commision number ?

Gene Ontology Molecular Function GO:0003677 DNA binding GO:0004879 nuclear receptor activity

	Biological Process
GO:0006355	regulation of DNA-templated transcription

	Cellular Component
GO:0005634	nucleus

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