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Structure of PDB 8d0k Chain B Binding Site BS01

Receptor Information >8d0k Chain B (length=362) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure] RCEEETPSLLWGLDPVFLAFAKLYIRDILDMKESRQVPGVFLYNGHPIKQ VDVLGTVIGVRERDAFYSYGVDDSTGVINCICWKKLNTESVSAAPSAARE LSLTSQLKKLQETIEQKTKIEIGDTIRVRGSIRTYREEREIHATTYYKVD DPVWNIQIARMLELPTIYRKVYDQPFHSSALEKEEALSNPGALDLPSLTS LLSEKAKEFLMENRVQSFYQQELEMVESLLSLANQPVIHSASSDQVNFKK DTTSKAIHSIFKNAIQLLQEKGLVFQKDDGFDNLYYVTREDKDLHRKIHR IIQQDCQKPNHMEKGCHFLHILACARLSIRPGLSEAVLQQVLELLEDQSD IVSTMEHYYTAF

Ligand information >8d0k Chain H (length=20) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure] tagggttagggttagggtta

Receptor-Ligand Complex Structure Global view Local view Structure summary [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] PDB 8d0k Structures of the human CST-Pol alpha-primase complex bound to telomere templates. Resolution 4.27 Å Binding residue (original residue number in PDB) L24 R67 R69 W89 R139 Y141 R142 Binding residue (residue number reindexed from 1) L18 R61 R63 W83 R133 Y135 R136

Enzymatic activity Enzyme Commision number ?

Gene Ontology Molecular Function GO:0003676 nucleic acid binding GO:0003677 DNA binding GO:0003697 single-stranded DNA binding GO:0005515 protein binding GO:0042162 telomeric DNA binding GO:0043047 single-stranded telomeric DNA binding

	Biological Process
GO:0000723	telomere maintenance
GO:0010833	telomere maintenance via telomere lengthening
GO:0016233	telomere capping
GO:0032211	negative regulation of telomere maintenance via telomerase
GO:0045740	positive regulation of DNA replication

	Cellular Component
GO:0000781	chromosome, telomeric region
GO:0001650	fibrillar center
GO:0005634	nucleus
GO:0005654	nucleoplasm
GO:0005694	chromosome
GO:0043231	intracellular membrane-bounded organelle
GO:0045111	intermediate filament cytoskeleton
GO:1990879	CST complex

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