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BioLiP

Structure of PDB 7xwp Chain B Binding Site BS01

Receptor Information
>7xwp Chain B (length=224) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LSPEQLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTKLADKELVHMISW
AKKIPGFVELSLFDQVRLLESSWMEVLMMGLMWRSIDHPGKLIFAPDLVL
DRDEGKSVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSDSSR
KLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGME
HLLNMKSKNVVPVYDLLLEMLNAH
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7xwp Evaluating the correlation of binding affinities between isothermal titration calorimetry and fragment molecular orbital method of estrogen receptor beta with diarylpropionitrile (DPN) or DPN derivatives.
Resolution1.919 Å
Binding residue
(original residue number in PDB)		I310 K314 E493
Binding residue
(residue number reindexed from 1)		I48 K52 E219
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:7xwp, PDBe:7xwp, PDBj:7xwp
PDBsum7xwp
PubMed35810932
UniProtQ92731|ESR2_HUMAN Estrogen receptor beta (Gene Name=ESR2)

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