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BioLiP

Structure of PDB 7n8n Chain B Binding Site BS01

Receptor Information
>7n8n Chain B (length=202) Species: 1560514 (Melbournevirus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RKRDKSVNFRLGLRNMLAQIHPDISVQTEALSELSNIAVFLGKKISHGAV
TLLPEGTKTIKSSAVLLAAGDLYGKDLGRHAVGEMTKAVTRYGSAKESKE
GSRSSKAKLQISVARSERLLREHGGCSRVSEGAAVALAAAIEYFMGEVLE
LAGNAARDSKKVRISVKHITLAIQNDAALFAVVGKGVFSGAGVSLISVPI
PR
Ligand information
>7n8n Chain I (length=125) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
tccggtgccgaggccgctcaattggtcgtagacagctctagcaccgctta
aacgcacgtacgcgctgtcccccgcgttttaaccgccaaggggattactc
cctagtctccaggcacgtgtcagat
Receptor-Ligand Complex Structure
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PDB7n8n Virus-encoded histone doublets are essential and form nucleosome-like structures.
Resolution3.89 Å
Binding residue
(original residue number in PDB)
K31 R32 N37 S54 Q56 K87 T88 K128 G130 S131 R132 A143 R192
Binding residue
(residue number reindexed from 1)
K2 R3 N8 S25 Q27 K58 T59 K99 G101 S102 R103 A114 R163
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Biological Process
GO:0030261 chromosome condensation
Cellular Component
GO:0000786 nucleosome
GO:0030430 host cell cytoplasm
GO:0042025 host cell nucleus
GO:0044423 virion component

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7n8n, PDBe:7n8n, PDBj:7n8n
PDBsum7n8n
PubMed34297924
UniProtA0A097I2B5|H2B2A_MELV Histone doublet H2B-H2A (Gene Name=MEL_369)

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