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Structure of PDB 6t0v Chain B Binding Site BS01

Receptor Information >6t0v Chain B (length=745) Species: 1129347 (Influenza A virus (A/little yellow-shouldered bat/Guatemala/060/2010(H17N10))) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure] MDVNPMLIFLKVPVQNAISTTFPYTGDPPYSHGTGTGYTMDTVIRTHDYS SRGIWKTNSETGAQQLNPIDGPLPEDNEPSGYAQTDCVLELIEGLDRSHP GLFETACQETIDAIQQTRVDKLTQGRQTYDWTLNRNQPAATALANTIEVF RKNGYKLNESGRLIDFLKDVLLSFENDSMEVTTHFQKKKRIRDNHSKKMI TQRTIGKKRVKLTKKNYLIRALTLNTMTKDAERGKLKRRAIATPGMQIRG FVYFVELLARNICERLEQSGLPVGGNEKKAKLANVIKKMMAKSTDEELSY TITGDNTKWNENQNPRIFLAMVLRITAGQPEWFRDLLAVAPIMFSNKVAR LGRGYMFESKSMHLRTQISAENLSDINLRYFNEDTKKKIEKIRHLMVEGT ASLSPGMMMGMFNMLSTVLGVSVLNLGQREILKRTYWWDGLQSSDDFALI INGHFKEDIQQGVNHFYRTCKLVGINMSQKKSYINKTGTFEFTSFFYRYG FVANFSMELPSFGVAGNNESADMSIGTTVIKTNMINNDLGPATAQMAIQL FIKDYRYTYRCHRGDTNLETRRTKSIKRLWTETISKAGLLVADGGPNPYN LRNLHIPEVCLKWSLMDPDYRGRLCNPNNPFVHHMEVESTKSLEYDAVAT THSWTPKRNRSILNTNQRGILEDERIYQKCCQVFEKFFPSSTYRRPIGMA SMLDAMLSRARIDARIDLESGRISSQDFSEITNTCKAIEALKRQG

Ligand information >6t0v Chain V (length=14) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure] aguaguaacaagag .<<....>>.....

Receptor-Ligand Complex Structure Global view Local view Structure summary [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] PDB 6t0v A Structure-Based Model for the Complete Transcription Cycle of Influenza Polymerase. Resolution 3.02 Å Binding residue (original residue number in PDB) H32 T34 Q186 D193 S196 K198 I200 R203 K237 M356 R365 I674 L675 N676 Binding residue (residue number reindexed from 1) H32 T34 Q186 D193 S196 K198 I200 R203 K237 M356 R365 I662 L663 N664

Enzymatic activity Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.

Gene Ontology Molecular Function GO:0000166 nucleotide binding GO:0003723 RNA binding GO:0003968 RNA-dependent RNA polymerase activity GO:0034062 5'-3' RNA polymerase activity

	Biological Process
GO:0001172	RNA-templated transcription
GO:0019083	viral transcription
GO:0039523	symbiont-mediated suppression of host mRNA transcription via inhibition of RNA polymerase II activity
GO:0039694	viral RNA genome replication

	Cellular Component
GO:0005737	cytoplasm
GO:0030430	host cell cytoplasm
GO:0042025	host cell nucleus

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