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●TM-score ●TM-align ●US-align ●MM-align ●RNA-align ●NW-align ●LS-align ●EDTSurf ●MVP ●MVP-Fit ●SPICKER ●HAAD ●PSSpred ●3DRobot ●MR-REX ●I-TASSER-MR ●SVMSEQ ●NeBcon ●ResPRE ●TripletRes ●DeepPotential ●WDL-RF ●ATPbind ●DockRMSD ●DeepMSA ●FASPR ●EM-Refiner ●GPU-I-TASSER

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Structure of PDB 6ee2 Chain B Binding Site BS01

Receptor Information >6ee2 Chain B (length=518) Species: 1036726 (Plasmodium falciparum NF135/5.C10) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure] SEVPQVVSLDPTSIPIEYNTPIHDIKVQVYDIKGGCNVEEGLTIFLVNNP GKENGPVKISSKVNDKQVSEFLKDENMEKFNVKLGTSKHFYMFNDNKNSV AVGYVGCGSVADLSEADMKRVVLSLVTMLHDNKLSKLTVVFEINVDKNLF RFFLETLFYEYMTDERFKSTDKNVNMEYIKHLGVYINNADTYKEEVEKAR VYYFGTYYASQLIAAPSNYCNPVSLSNAAVELAQKLNLEYKILGVKELEE LKMGAYLSVGKGSMYPNKFIHLTYKSKGDVKKKIALVGKGITFDSGGYNL KAAPGSMIDLMKFDMSGCAAVLGCAYCVGTLKPENVEIHFLSAVCENMVS KNSYRPGDIITASNGKTIEVGNTDAEGRLTLADALVYAEKLGVDYIVDIA TLTGAMLYSLGTSYAGVFGNNEELINKILQSSKTSNEPVWWLPIINEYRA TLNSKYADINQISSSVKASSIVASLFLKEFVQNTAWAHIDIAGVSWNFKA RKPKGFGVRLLTEFVLND

Ligand information Ligand ID CO3 InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-2 InChIKey BVKZGUZCCUSVTD-UHFFFAOYSA-L SMILES Software SMILES OpenEye OEToolkits 1.5.0 C(=O)([O-])[O-] ACDLabs 10.04 CACTVS 3.341 [O-]C([O-])=O Formula C O3 Name CARBONATE ION ChEMBL DrugBank DB14531 ZINC PDB chain 6ee2 Chain B Residue 701 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure Global view Local view Structure summary [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] PDB 6ee2 Hydroxamic Acid Inhibitors Provide Cross-Species Inhibition of Plasmodium M1 and M17 Aminopeptidases. Resolution 2.1 Å Binding residue (original residue number in PDB) A460 G462 R463 L487 Binding residue (residue number reindexed from 1) A375 G377 R378 L402 Annotation score 3

Enzymatic activity Enzyme Commision number 3.4.11.1: leucyl aminopeptidase.

Gene Ontology Molecular Function GO:0030145 manganese ion binding GO:0046872 metal ion binding GO:0070006 metalloaminopeptidase activity

	Biological Process
GO:0006508	proteolysis
GO:0019538	protein metabolic process

	Cellular Component
GO:0005737	cytoplasm

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