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Structure of PDB 5krb Chain B Binding Site BS01

Receptor Information
>5krb Chain B (length=74) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QRTCLICGDRATGLHYGIISCEGCKGFFKRSISNKRVYRCSRDKNCVMSR
KQRNRCQYCRLLKCLQMGMNRKAI
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5krb A Structural Investigation into Oct4 Regulation by Orphan Nuclear Receptors, Germ Cell Nuclear Factor (GCNF), and Liver Receptor Homolog-1 (LRH-1).
Resolution2.101 Å
Binding residue
(original residue number in PDB)		L85 H86 Y87 K96 K100
Binding residue
(residue number reindexed from 1)		L14 H15 Y16 K25 K29
Binding affinityPDBbind-CN: Kd=170nM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0008270 zinc ion binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:5krb, PDBe:5krb, PDBj:5krb
PDBsum5krb
PubMed27984042
UniProtQ64249|NR6A1_MOUSE Nuclear receptor subfamily 6 group A member 1 (Gene Name=Nr6a1)

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