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BioLiP

Structure of PDB 5dlr Chain B Binding Site BS01

Receptor Information
>5dlr Chain B (length=240) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQGKEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNS
GVYTFLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLI
LSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHRLH
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5dlr Predictive features of ligand-specific signaling through the estrogen receptor.
Resolution2.26 Å
Binding residue
(original residue number in PDB)		I358 K362 L372 Q375 V376 E380 L539 E542
Binding residue
(residue number reindexed from 1)		I54 K58 L68 Q71 V72 E76 L229 E232
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5dlr, PDBe:5dlr, PDBj:5dlr
PDBsum5dlr
PubMed27107013
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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