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Structure of PDB 1c0w Chain B Binding Site BS01

Receptor Information >1c0w Chain B (length=219) Species: 1717 (Corynebacterium diphtheriae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure] KDLVDTTEMYLRTIYELEEEGVTPLRARIAERLEQSGPTVSQTVARMERD GLVVVASDRSLQMTPTGRTLATAVMRKHRLAERLLTDIIGLDINKVHDEA CRWEHVMSDEVERRLVKVLKDVSRSPFGNPIPGLDELGVAPGTRVIDAAT SMPRKVRIVQINEIFQVETDQFTQLLDADIRVGSEVEIVDRDGHITLSHN GKDVELLDDLAHTIRIEEL

Ligand information >1c0w Chain E (length=21) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure] attaggttagcctaccctaat

Receptor-Ligand Complex Structure Global view Local view Structure summary [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] PDB 1c0w Crystal structure of a cobalt-activated diphtheria toxin repressor-DNA complex reveals a metal-binding SH3-like domain. Resolution 3.2 Å Binding residue (original residue number in PDB) T7 Q36 S37 P39 T40 Q43 R47 R50 Binding residue (residue number reindexed from 1) T6 Q35 S36 P38 T39 Q42 R46 R49

Enzymatic activity Enzyme Commision number ?

Gene Ontology Molecular Function GO:0003677 DNA binding GO:0003700 DNA-binding transcription factor activity GO:0017124 SH3 domain binding GO:0042802 identical protein binding GO:0046914 transition metal ion binding GO:0046983 protein dimerization activity

	Biological Process
GO:0006355	regulation of DNA-templated transcription
GO:0045892	negative regulation of DNA-templated transcription

	Cellular Component
GO:0005737	cytoplasm

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