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Structure of PDB 6z4v Chain AAA Binding Site BS01

Receptor Information >6z4v Chain AAA (length=456) Species: 10116 (Rattus norvegicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure] NSDLDVNTDIYSKVLVTAIYLALFVVGTVGNGVTLFTLARKRVDYYLGSL ALSDLLILLFALPVELYNFIWVHHPWAFGDAGCKGYYFLRDACTYATALN VVSLSVELYLAICRTKKFISAIWLASALLAIPMLFTMGLQNLSGDGTHPG GLVCTPIVDTATLRVVIQLNTFMSFLFPMLVASILNTVAARRLTVMVHQA AFNMTIEPGRVQALRRGVLVLRAVVIAFVVCWLPYHVRRLMFVYISDEQW TTALFDFYHYFYMLSNALFYVSSAINPILYNLAEDLVEDWEKARKLLEAA RKGQDDEVRILLANGADVNTADETGFTPLHLAAWEGHLGIVEVLLKNGAD VNANDERGHTPLHLAAYTGHLEIVEVLLKNGAGVNATDVIGTAPLHLAAM WGHLEIVEVLLKNGADVNAQDKFGKTPFDLAIDNGNEDIAEVLQKAATRE LEVLFQ

Ligand information >6z4v Chain BBB (length=5) Species: 10116 (Rattus norvegicus) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure] RPYIL

Receptor-Ligand Complex Structure Global view Local view Structure summary [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] PDB 6z4v Complexes of the neurotensin receptor 1 with small-molecule ligands reveal structural determinants of full, partial, and inverse agonism. Resolution 2.595 Å Binding residue (original residue number in PDB) L55 F128 H132 Y146 V224 T226 R327 R328 F331 S335 W339 F344 Y347 Binding residue (residue number reindexed from 1) L4 F69 H73 Y87 V153 T155 R238 R239 F242 S246 W250 F255 Y258

Enzymatic activity Enzyme Commision number ?

Gene Ontology Molecular Function GO:0004930 G protein-coupled receptor activity GO:0016492 G protein-coupled neurotensin receptor activity

	Biological Process
GO:0007186	G protein-coupled receptor signaling pathway

	Cellular Component
GO:0016020	membrane

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