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●I-TASSER ●I-TASSER-MTD ●C-I-TASSER ●CR-I-TASSER ●QUARK ●C-QUARK ●LOMETS ●MUSTER ●CEthreader ●SEGMER ●DeepFold ●DeepFoldRNA ●FoldDesign ●COFACTOR ●COACH ●MetaGO ●TripletGO ●IonCom ●FG-MD ●ModRefiner ●REMO ●DEMO ●DEMO-EM ●SPRING ●COTH ●Threpp ●PEPPI ●BSpred ●ANGLOR ●EDock ●BSP-SLIM ●SAXSTER ●FUpred ●ThreaDom ●ThreaDomEx ●EvoDesign ●BindProf ●BindProfX ●SSIPe ●GPCR-I-TASSER ●MAGELLAN ●ResQ ●STRUM ●DAMpred

●TM-score ●TM-align ●US-align ●MM-align ●RNA-align ●NW-align ●LS-align ●EDTSurf ●MVP ●MVP-Fit ●SPICKER ●HAAD ●PSSpred ●3DRobot ●MR-REX ●I-TASSER-MR ●SVMSEQ ●NeBcon ●ResPRE ●TripletRes ●DeepPotential ●WDL-RF ●ATPbind ●DockRMSD ●DeepMSA ●FASPR ●EM-Refiner ●GPU-I-TASSER

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Structure of PDB 5kyu Chain A Binding Site BS01

Receptor Information >5kyu Chain A (length=716) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure] TYLEFIQQNEERDGVRFSWNVWPSSRLEATRMVVPVAALFTPLKERPDLP PIQYEPVLCSRTTCRAVLNPLCQVDYRAKLWACNFCYQRNQFPPSYAGIS ELNQPAELLPQFSSIEYVVLRGPQMPLIFLYVVDTCMEDEDLQALKESMQ MSLSLLPPTALVGLITFGRMVQVHELGCEGISKSYVFRGTKDLSAKQLQE MLGLSKVSNRFLQPVQKIDMNLTDLLGELQRDPWPVPQGKRPLRSSGVAL SIAVGLLECTFPNTGARIMMFIGGPATQGPGMVVGDELKTPIRSWHDIDK DNAKYVKKGTKHFEALANRAATTGHVIDIYACALDQTGLLEMKCCPNLTG GYMVMGDSFNTSLFKQTFQRVFTKDMHGQFKMGFGGTLEIKTSREIKISG AIGPCVSLNSKGPCVSENEIGTGGTCQWKICGLSPTTTLAIYFEVVGRGA IQFVTQYQHSSGQRRIRVTTIARNWADAQTQIQNIAASFDQEAAAILMAR LAIYRAETEEGPDVLRWLDRQLIRLCQKFGEYHKDDPSSFRFSETFSLYP QFMFHLRRSSFLQVFNNSPDESSYYRHHFMRQDLTQSLIMIQPILYAYSF SGPPEPVLLDSSSILADRILLMDTFFQILIYHGETIAQWRKSGYQDMPEY ENFRHLLQAPVDDAQEILHSRFPMPRYIDTEHGGSQARFLLSKVPILTDD VSLQVFMDHLKKLAVS

Ligand information >5kyu Chain C (length=3) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure] PPP

Receptor-Ligand Complex Structure Global view Local view Structure summary [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] PDB 5kyu TANGO1/cTAGE5 receptor as a polyvalent template for assembly of large COPII coats. Resolution 3.512 Å Binding residue (original residue number in PDB) W667 Y672 Y678 Binding residue (residue number reindexed from 1) W639 Y644 Y650

Enzymatic activity Enzyme Commision number ?

Gene Ontology Molecular Function GO:0005096 GTPase activator activity GO:0005515 protein binding GO:0008270 zinc ion binding GO:0046872 metal ion binding

	Biological Process
GO:0006886	intracellular protein transport
GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport
GO:0015031	protein transport
GO:0016192	vesicle-mediated transport
GO:0072659	protein localization to plasma membrane
GO:0090110	COPII-coated vesicle cargo loading
GO:0090114	COPII-coated vesicle budding

	Cellular Component
GO:0000139	Golgi membrane
GO:0005737	cytoplasm
GO:0005783	endoplasmic reticulum
GO:0005789	endoplasmic reticulum membrane
GO:0005829	cytosol
GO:0012507	ER to Golgi transport vesicle membrane
GO:0016020	membrane
GO:0030127	COPII vesicle coat
GO:0030134	COPII-coated ER to Golgi transport vesicle
GO:0031410	cytoplasmic vesicle
GO:0048471	perinuclear region of cytoplasm
GO:0070971	endoplasmic reticulum exit site

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View graph for Cellular Component