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BioLiP

Structure of PDB 3fhz Chain A Binding Site BS01

Receptor Information
>3fhz Chain A (length=155) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ANRAGRQARIVAILSSAQVRSQNELAALLAAEGIEVTQATLSRDLEELGA
VKLRGADGGTGIYVVPEDGSPVRGVSGGTDRMARLLGELLVSTDDSGNLA
VLRTPPGAAHYLASAIDRAALPQVVGTIAGDDTILVVAREPTTGAQLAGM
FENLR
Ligand information
Receptor-Ligand Complex Structure
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PDB3fhz The structure of the arginine repressor from Mycobacterium tuberculosis bound with its DNA operator and Co-repressor, L-arginine.
Resolution3.27 Å
Binding residue
(original residue number in PDB)
S36 Q37 Q53 S57 R58 Y78
Binding residue
(residue number reindexed from 1)
S21 Q22 Q38 S42 R43 Y63
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0034618 arginine binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006525 arginine metabolic process
GO:0006526 L-arginine biosynthetic process
GO:0051259 protein complex oligomerization
GO:1900079 regulation of arginine biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function

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Cellular Component
External links
PDB RCSB:3fhz, PDBe:3fhz, PDBj:3fhz
PDBsum3fhz
PubMed19265706
UniProtP9WPY9|ARGR_MYCTU Arginine repressor (Gene Name=argR)

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