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BioLiP

Structure of PDB 2olg Chain A Binding Site BS01

Receptor Information
>2olg Chain A (length=276) Species: 33394 (Holotrichia diomphalia) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RNRRPELLPNDCGYQVEADKILNGDDTVPEEFPWTAMIGYKNSSNFEQFA
CGGSLINNRYIVTAAHCVAGRVLRVVGALNKVRLGEWNTATDPDCYGAVR
VCVPDKPIDLGIEETIQHPDYVDGSKDRYHDIALIRLNRQVEFTNYIRPV
CLPQPNEEVQVGQRLTVVGWGRTETGQYSTIKQKLAVPVVHAEQCAKTFG
AAGVRVRSSQLCAGGEKAKDSCGGDSGGPLLAERANQQFFLEGLVSFGAT
CGTEGWPGIYTKVGKYRDWIEGNIRP
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain2olg Chain A Residue 2001 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2olg Crystal structure of the serine protease domain of prophenoloxidase activating factor-I
Resolution1.7 Å
Binding residue
(original residue number in PDB)		E175 N177 T180 D183
Binding residue
(residue number reindexed from 1)		E86 N88 T91 D94
Annotation score4
Enzymatic activity
Catalytic site (original residue number in PDB) H155 D220 G312 G313 D314 S315 G316
Catalytic site (residue number reindexed from 1) H66 D131 G223 G224 D225 S226 G227
Enzyme Commision number 3.4.21.-
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:2olg, PDBe:2olg, PDBj:2olg
PDBsum2olg
PubMed17287215
UniProtO97366|PPAF1_HOLDI Phenoloxidase-activating factor 1 (Gene Name=PPAF1)

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