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BioLiP

Structure of PDB 2hoi Chain A Binding Site BS01

Receptor Information
>2hoi Chain A (length=322) Species: 10678 (Punavirus P1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SDEVRKNLMDMFRDRQAFSEHTWKMLLSVCRSWAAWCKLNNRKWFPAEPE
DVRDYLLYLQARGLAVKTIQQHLGQLNMLHRRSGLPRPSDSNAVSLVMRR
IRKENVDAGERAKQALAFERTDFDQVRSLMENSDRCQDIRNLAFLGIAYN
TLLRIAEIARIRVKDISRTDGGRMLIHIGRTATLVSTAGVEKALSLGVTK
LVERWISVSGVADDPNNYLFCRVRKNGVAAPSATSQLSTRALEGIFEATH
RLIYGAKDDSGQRYLAWSGHSARVGAARDMARAGVSIPEIMQAGGWTNVN
IVMNYIRNLDSETGAMVRLLED
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2hoi Synapsis of loxP sites by Cre recombinase.
Resolution2.601 Å
Binding residue
(original residue number in PDB)		F37 S38 H40 T41 Q90 M97 I174 A175 R243 K244 N245 R259 E262 K276 R282 Y283 S287 G288 H289
Binding residue
(residue number reindexed from 1)		F18 S19 H21 T22 Q71 M78 I155 A156 R224 K225 N226 R240 E243 K257 R263 Y264 S268 G269 H270
Binding affinityPDBbind-CN: Kd=8.9nM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006310 DNA recombination
GO:0015074 DNA integration

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Molecular Function
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Biological Process
External links
PDB RCSB:2hoi, PDBe:2hoi, PDBj:2hoi
PDBsum2hoi
PubMed17573343
UniProtP06956|RECR_BPP1 Recombinase cre (Gene Name=cre)

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