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●I-TASSER ●I-TASSER-MTD ●C-I-TASSER ●CR-I-TASSER ●QUARK ●C-QUARK ●LOMETS ●MUSTER ●CEthreader ●SEGMER ●DeepFold ●DeepFoldRNA ●FoldDesign ●COFACTOR ●COACH ●MetaGO ●TripletGO ●IonCom ●FG-MD ●ModRefiner ●REMO ●DEMO ●DEMO-EM ●SPRING ●COTH ●Threpp ●PEPPI ●BSpred ●ANGLOR ●EDock ●BSP-SLIM ●SAXSTER ●FUpred ●ThreaDom ●ThreaDomEx ●EvoDesign ●BindProf ●BindProfX ●SSIPe ●GPCR-I-TASSER ●MAGELLAN ●ResQ ●STRUM ●DAMpred

●TM-score ●TM-align ●US-align ●MM-align ●RNA-align ●NW-align ●LS-align ●EDTSurf ●MVP ●MVP-Fit ●SPICKER ●HAAD ●PSSpred ●3DRobot ●MR-REX ●I-TASSER-MR ●SVMSEQ ●NeBcon ●ResPRE ●TripletRes ●DeepPotential ●WDL-RF ●ATPbind ●DockRMSD ●DeepMSA ●FASPR ●EM-Refiner ●GPU-I-TASSER

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Structure of PDB 1e3p Chain A Binding Site BS01

Receptor Information >1e3p Chain A (length=645) Species: 1890 (Streptomyces antibioticus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure] NETHYAEAVIDNGAFGTRTIRFETGRLARQAAGSAVAYLDDDTMVLSATT ASKNPKDQLDFFPLTVDVEERMYAAGKIPGSFFRREGRPSEDAILTCRLI DRPLRPSFKKGLRNEIQVVATIMALNPDHLYDVVAINAASASTQLAGLPF SGPIGGVRVALIRGQWVAFPTHTELEDAVFDMVVAGRVLEDGDVAIMMVE AEATEKTIQLVKDGAEAPTEEVVAAGLDAAKPFIKVLCKAQADLAAKAAK PTGEFPVFLDYQDDVLEALSAAVRPELSAALTIAGKQDREAELDRVKALA AEKLLPEFEGREKEISAAYRALTKSLVRERVIAEKKRIDGRGVTDIRTLA AEVEAIPRVHGSALFERGETQILGVTTLNMLRMEQQLDTLSPVTRKRYMH NYNFPPYSVGETGRVGSPKRREIGHGALAERAIVPVLPTREEFPYAIRQV SEALGSNGSTSMGSVCASTMSLLNAGVPLKAPVAGIAMGLISQEINGETH YVALTDILGAEDAFGDMDFKVAGTKEFVTALQLDTKLDGIPASVLAAALK QARDARLHILDVMMEAIDTPDEMSPNAPRIITVNQIQEDTGAEIYIGAAD GPAAEAGSVVKTTFGAFVSLLDGLLHLGVGQKVQVEIAEIDSRGK

Ligand information Ligand ID WO4 InChI InChI=1S/4O.W/q;;2*-1; InChIKey PBYZMCDFOULPGH-UHFFFAOYSA-N SMILES Software SMILES OpenEye OEToolkits 1.5.0 [O-][W](=O)(=O)[O-] ACDLabs 10.04 CACTVS 3.341 [O-][W]([O-])(=O)=O Formula O4 W Name TUNGSTATE(VI)ION ChEMBL DrugBank ZINC PDB chain 1e3p Chain A Residue 911 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure Global view Local view Structure summary [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] PDB 1e3p A Duplicated Fold is the Structural Basis for Polynucleotide Phosphorylase Catalytic Activity, Processivity, and Regulation Resolution 2.5 Å Binding residue (original residue number in PDB) H427 S461 T462 S463 Binding residue (residue number reindexed from 1) H425 S459 T460 S461 Annotation score 1

Enzymatic activity Enzyme Commision number 2.7.7.8: polyribonucleotide nucleotidyltransferase.

Gene Ontology Molecular Function GO:0000175 3'-5'-RNA exonuclease activity GO:0000287 magnesium ion binding GO:0003676 nucleic acid binding GO:0003723 RNA binding GO:0004654 polyribonucleotide nucleotidyltransferase activity GO:0016779 nucleotidyltransferase activity GO:0046872 metal ion binding

	Biological Process
GO:0006396	RNA processing
GO:0006401	RNA catabolic process
GO:0006402	mRNA catabolic process

	Cellular Component
GO:0005737	cytoplasm
GO:0005829	cytosol

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