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Structure of PDB 8wib Chain 2 Binding Site BS01

Receptor Information >8wib Chain 2 (length=63) Species: 246196 (Mycolicibacterium smegmatis MC2 155) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure] TTPGELRELTDDELKDKLRESKEELFNLRFQMATGQLSNNRRLRTVRQEI ARVYTVLRERELG

Ligand information >8wib Chain A (length=3022) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure] aaguguuuaagggcgcaugguggaugccuuggcacugggagccgaugaag gacguaggaggcugcgauaagccucggggagcugucaaccgagcguugau ccgaggauguccgaauggggaaacccggcacgagugaugucgugucacca ggcgcugaauauauaggcgucuggggggaacgcggggaagugaaacaucu caguacccguaggaagagaaaacaaaaugugauuccgugaguaguggcga gcgaaagcggaggauggcuaaaccguaugcaugugauaccggguaggggu ugugugugcgggguugugggaccuaucuuuccggcucuaccuggcuggag ggcagugagaaaauguugugguuagcggaaauggcuugggauggccugcc guagacggugagagcccgguacgugaaaacccgacgucugucuugauggu guucccgaguagcagcgggcccguggaaucugcugugaaucugccgggac cacccgguaagccugaauacuucccagugaccgauagcggauuaguaccg ugagggaauggugaaaaguaccccgggaggggagugaaagaguaccugaa accgugcgcuuacaauccgucagagcccucgacgugucguggggugaugg cgugccuuuugaagaaugagccugcgagucagggacaugucgcgagguua acccgggugggguagccgcagcgaaagcgagucugaauagggcguaucca cacaagagugugugguguagugguguguucuggacccgaagcggagugau cuacccauggccagggugaagcgcggguaagaccgcguggaggcccgaac ccacuuagguugaagacugaggggaugagcuguggguaggggugaaaggc caaucaaacuccgugauagcugguucuccccgaaaugcauuuaggugcag cgucgcauguuucuugccggagguagagcuacuggauggccgaugggccc cacaggguuacugacgucagccaaacuccgaaugccgguaaguccaagag ugcggcagugagacggcgggggauaagcuccgugcgucgagagggaaaca gcccagaucgccggcuaaggccccuaagcgugugcuaaguggaaaaggau gugcagucgcgaagacaacacuggucaagugauugugcgccgauaaugua gcggggcucaagcacaccgccgaagccgcggcagccaacguguuggcugg guaggggagcguccugcauccggugaagccgccgagugaucgaguggugg agggugugggagugagaaugcaggcaugaguagcgauuaggcaagugaga accuugcccgccgaaagaccaaggguuccugggccaggccaguccgccca gggugagucgggaccuaaggcgaggccgacaggcguagucgauggacaac ggguugauauucccguacccguguaugugcguccaugaugaaucagcggu acuaaccaucgcugcaugggaccuucguugguaguagucaagcgaugggg ugacgcaggaagguagccguaccggucagugguaauaccgggguaagccu guagggagucagauagguaaauccgucuggcauauauccugagaggugau gcauagccgagugaggcgaauucggugauccuaugcugccgagaaaagcc ucuagcgaggacauacacggcccguaccccaaaccaacacagguggucag guagagaauacuaaggcguacgagugaacuaugguuaaggaacucggcaa aaugcccccguaacuucgggagaagggggacccacauggcguguaagccu uuacggcccaagcgugaguggguggcacaaaccagugagaagcgacuguu uacuaaaaacacagguccgugcgaagucgcaagacgauguauacggacug acgccugcccggugcuggaagguuaagaggacccguuaacucccuuuggg ggugaagcggagaauuuaagccccaguaaacggcggugguaacuauaacc auccuaagguagcgaaauuccuugucggguaaguuccgaccugcacgaau ggcguaacgacuucucaacugucucaaccauagacucggcgaaauugcac uacgaguaaagaugcucguuacgcgcggcaggacgaaaagaccccgggac cuucacuacaacuugguauuggugcucgauacgguuuguguaggauaggu gggagacugugaagcucacacgccaguguggguggagucguuguugaaau accacucugaucguauugggccucuaaccucggaccguauauccgguuca gggacagugccugguggguaguuuaacuggggcgguugccuccuaaaaug uaacggaggcgcccaaagguucccucaaccuggacggcaaucagguguug aguguaagugcacaagggagcuugacugcgagacggacaugucgagcagg gacgaaagucgggacuagugauccggcaccucugaguggaaggggugucg cucaacggauaaaagguaccccggggauaacaggcugaucuuccccaaga gauaucgacgggaugguuuggcaccucgaugucggcucgucgcauccugg ggcuggagcaggucccaaggguugggcuguucgcccauuaaagcggcacg cgagcuggguuuagaacgucgugagacaguucggucucuauccgccgcgc gcgucagaagcuugaggaaaccugucccuaguacgagaggaccgggacgg acgaaccucugguauaccaguugucccaccaggggcacggcuggauagcc acguucggacaggauaaccgcugaaagcaucuaagcgggaaaccucuucc aagaccaggcuucucacccucuaggagggauaaggccccccgcagaccac gggauugauagaccagaccuggaagccuaguaauaggugcagggaacugg cacuaaccggccgaaaacuuac <<<<......<<<<<<<<<<<.....<<..<<<<<<<<<<<<<......< <<<<<.[[.(((.>>>.....<<<<<<<..<<<)))..]].>>>.....> >>>>>>...>>>....<<<....>>><<<<<<<......>>>>>>>.<<< <<<<<<.........>>>>>>>>>.>>...<<<<<<.....<<....>>. .....>>>>>.>.........<<.....>>..<<<<<<.....<<..... >>....>>>>>>...<<<....<<<<<<<<<<.........(((((.... .>>>>>>>>>>......<<<<<.<.....<<<<<<<))))).>>>>>>>< <<<<<.......<<<<<<.<<<<.<<<.....<<<<......>>>>.((. .....<<<.....))>>>...>>>...>>>>>>>>>>>>>>>>.....>. >.>>>>.....<<<<<<<<.........>>>>>>>>......<<<<<..< <<<>>>>>..>>>......>>.>>>>>>>.>>...............<<. ...>>....>>.........<<<<....>>>>.................. >>>>>>>>>>>.......<<<<..<<<<<<<<<..>>>>.>>>>>..>>> >...<.<........>.>.<<<<<<....<<<.<<<<<<<<<<..<<<.. .<<<....>>>...>>>...<<....>>..<<<<.....>>>>....<<< <<<<....>>>>>>>....>>>>>>>>>>>>>..<<.<..<<<<<<<... ..<<<<<<<<<..<<<....<<<<<<......>>>>>>.....>>>...< <<.<<<<<........>>>>>>>>....>>>>>>>>>...<<<.....>> >......>>>>>>...>..>.>>..<<<<<<....<<<<<....>>>>>< <<<<<<<<....<<<<<<<<.....<<<....<<<.<.<<......<<<< ....>>>>.......>>.>.>>>..>>.>.....>>>>>>>>.......> >>>>>>.>>..<<<<<<<<<<......>>>>>>.>>>>....<<<..... .>>>...<<<<.<<<...<<<(((.....<<<<<<...........<<.. <<<<<<<<<........<......>....>>>>>>>>>.>>......... ..)))......>>>>>>.>>>...>>>>>>><<<<<<<<..>>>>>>>>. ...>>>>>><.<<<<<<<<<<......<<<<<<<<....>>>.>>>>>.. .>>>>>>>>>>..>.....>>>>>><......<<.....<<<<<<..... ..>>>>>><<<<....<<<<<.<<...<<<<<<...<<.....>>.>>>> >>....((<<<<.<<...<<<...<<<....>>>...>>>...>>...<< <<<........>>>>>))<<<<<<<<<<.......<<<<...<<<<<<<. .....<<<<......>>>>.....>>>>>>>.....>>>>.<<...<<<< <...<<<<..<<<..<<<<..<<<<<...((((...>>>>>.<<..<<<< ...<<<<<<<<<<<.<<.....>>>>>>>>>.....>>>>...>>>>... >>...<<<......>>>.....>>>>...>>>...>>>>........>>> >>..>>....>>>>>>>>>>>>>>..>>.....<<......>>>>>>>.< <<<.....>>>>..>>>>..<<<<<...<<<<<<<<.<<.........<. ....<<<<<.....<..>......>>>>><<<<<<...<<<<....<<<. ....>>>....>>>>..>>>>>>............<<<<<<<<<..<<<. ........>>>..<<<<<<<.....<<<....>>>.......>>>>>>>. <<<<<.<<<..<<<<<<<..<<<<..<<....<<<<..<<<<<<...>>> >>>...>>>>....>>..>>>>>>>>>..>>>>><<<<<<.......>>> >>>........<...........<<<<<<.....>>>>>>.....>.... >>>>>..>>.>>>>>>>..>..>>.>>>>>>>>>>>>>>>.....>.((. .<<<<<......))>>>>>..<<<<<<<<.<<<.<<......<<<<<<<< <<..<<<<<.<<<.<<<<<.<<.<<<<<<<<<<<...............< <<..<<<......<<<<<<<<....>>>>>>>>...>>>........... .>>>......>>>>>>>>>>>.>>...<<<.<<<<<<......>>>>>>> >>....>>>>>.>>>..>>>>>..<<<<.....>>>><<<<<<....... ....>>>>>>..<<...<<<<<<<...<<<<<<.......>>>>>>.... .<<.[.(((>>....>>>>>>>...<<<<..<<<<....>>>>..>>>>. <<<....>>>.>>)))]......<<<<<<<.<<..>>>>..>>>>>>>>> .............>>>>..>>>>>>.......<<<<...<.<<<<...<< ....>>...>>>>.>....>>>.>.......<<<<<.<<<<<<..<<<<< <<<<......>>>>>>..>>>.<<<<<.....>>>>>.....>>>>>..> ...>>>.>>....<<<<<<<....>>>.>>>>....>>..>>>>>>>>>> >....<<<<<<<...<<<<..<<<<<<<...............>>>>>>> .<<<<<...<<<<...<<<<<<<<<<<))))>>>>>>..>>>>>...>>> >.>>>>>...<<<....<<<<<...........>>>>>....>>>.>>>> .......>>>>>>>..<<<<<...>>>>>....<<<<.<<<<.......> >>>.....<<<.<<<<.<<<....<<<<<....>>>>>...>>>..>>>> ..>>>...>>>>....>>>>..

Receptor-Ligand Complex Structure Global view Local view Structure summary [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] PDB 8wib Cryo- EM structure of the mycobacterial 70S ribosome in complex with ribosome hibernation promotion factor RafH. Resolution 3.5 Å Binding residue (original residue number in PDB) R11 N43 N44 R45 R51 R56 T59 R62 Binding residue (residue number reindexed from 1) R7 N39 N40 R41 R47 R52 T55 R58

Enzymatic activity Enzyme Commision number ?

Gene Ontology Molecular Function GO:0003735 structural constituent of ribosome

	Biological Process
GO:0006412	translation

	Cellular Component
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:1990904	ribonucleoprotein complex

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View graph for Cellular Component