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BioLiP

Structure of PDB 1c8m Chain 1 Binding Site BS01

Receptor Information
>1c8m Chain 1 (length=285) Species: 31708 (rhinovirus A16) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NPVERYVDEVLNEVLVVPNINQSHPTTSNAAPVLDAAETGHTNKIQPEDT
IETRYVQSSQTLDEMSVESFLGRSGCIHESVLDIVDNYNDQSFTKWNINL
QEMAQIRRKFEMFTYARFDSEITMVPSVAAKDGHIGHIVMQYMYVPPGAP
IPTTRDDYAWQSGTNASVFWQHGQPFPRFSLPFLSIASAYYMFYDGYDGD
TYKSRYGTVVTNDMGTLCSRIVTSEQLHKVKVVTRIYHKAKHTKAWCPRP
PRAVQYSHTHTTNYKLSSEVHNDVAIRPRTNLTTV
Ligand information
>1c8m Chain 4 (length=29) Species: 31708 (rhinovirus A16) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
GAQVSRQSINYFNINYFKDAASSGASRLD
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1c8m Structure of a Human Common Cold Virus and Functional Relationship to Other Picornaviruses
Resolution2.8 Å
Binding residue
(original residue number in PDB)		V3 Y6 E9 D63 S66 E68 S180 K241 H242
Binding residue
(residue number reindexed from 1)		V3 Y6 E9 D63 S66 E68 S180 K241 H242
Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
3.4.22.28: picornain 3C.
3.4.22.29: picornain 2A.
3.6.1.15: nucleoside-triphosphate phosphatase.
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity

View graph for
Molecular Function
External links
PDB RCSB:1c8m, PDBe:1c8m, PDBj:1c8m
PDBsum1c8m
PubMed
UniProtQ82122|POLG_HRV16 Genome polyprotein

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